FGF-13 rabbit pAb

• Background:

  The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008]

• Description:

  The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008],

• Synonyms:

  FGF13; FHF2; Fibroblast growth factor 13; FGF-13; Fibroblast growth factor homologous factor 2; FHF-2

• Gene ID:

  2258

• UniProt:

  Q92913

• Cellular Locus:

  [Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm. Nucleus.; [Isoform 3]: Cytoplasm. Nucleus.; [Isoform 4]: Cytoplasm. Nucleus.; [Isoform 5]: Cytoplasm. Nucleus.; Cell projection, filopodium. Cell projection, growth cone. Cell projection, dendrite. Cell membrane, sarcolemma. Cytoplasm. Not secreted. Localizes to the lateral membrane and intercalated disks of myocytes..

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human FGF13. AA range:154-203

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA

• Validated Applications:

  WB, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

• Molecular Weight:

  28kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  28 kD

• Subcellular Location:

  [Isoform 1]: Nucleus .; [Isoform 2]: Cytoplasm . Nucleus .; [Isoform 3]: Cytoplasm . Nucleus .; [Isoform 4]: Cytoplasm . Nucleus .; [Isoform 5]: Cytoplasm . Nucleus .; Cell projection, filopodium . Cell projection, growth cone . Cell projection, dendrite . Cell membrane, sarcolemma . Cytoplasm . Not secreted. Localizes to the lateral membrane and intercalated disks of myocytes. .

• Other Product Names:

  FGF13; FHF2; Fibroblast growth factor 13; FGF-13; Fibroblast growth factor homologous factor 2; FHF-2

• Gene ID (Human):

  2258

• SwissProt (Human):

  Q92913