Products for Research Use Only
RegisterLogin

FoxK1 rabbit pAb

CAT: 0855-ES5233-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES5233-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Function:Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli., PTM:Phosphorylated., similarity:Contains 1 FHA domain., similarity:Contains 1 fork-head DNA-binding domain., subunit:Interacts with SIN3B to form a complex which represses transcription., tissue specificity:Expressed both developing and adult tissues. In adults, significant expression is seen in tumors of the brain, colon and lymph node.
Description
Function: Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli. PTM: Phosphorylated. similarity: Contains 1 FHA domain. similarity: Contains 1 fork-head DNA-binding domain. subunit: Interacts with SIN3B to form a complex which represses transcription. tissue specificity: Expressed both developing and adult tissues. In adults, significant expression is seen in tumors of the brain, colon and lymph node.
UniProt
P85037
Swiss Prot
P85037
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human FOXK1. AA range:681-730
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
78kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
78kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . Translocation to the nucleus is regulated by phosphorylation: phosphorylation by GSK3 (GSK3A or GSK3B) promotes interaction with 14-3-3 proteins and sequestration in the cytoplasm. Dephosphorylation promotes translocation to the nucleus (By similarity) . Accumulates in the nucleus upon viral infection (PubMed:25852164) . .
Other Product Names
FOXK1; MNF; Forkhead box protein K1; Myocyte nuclear factor; MNF
Gene ID (Human)
221937

Related Products

CatalogName
ES2363-01FoxL1 rabbit pAb
ES16344-01FOXG1 rabbit pAb
ES5303-01FoxO1 rabbit pAb
ES3943-01FOXP1 rabbit pAb
ES16326-01FOXQ1 rabbit pAb
ES10883-01FOXF1 rabbit pAb
ES9024-01FOXN1 rabbit pAb
ES5299-01FoxE1 rabbit pAb
ES9050-01FOXM1 rabbit pAb
ES19781-01FOXK2 rabbit pAb

Alternative Products

CatalogName
E2160358FOXK1 Rabbit pAb
GTR18219056-01Rabbit FOXK1 Antibody
A27583-01FOXK1 Rabbit mAb
NBP2-98879-50ulRabbit Polyclonal FoxK1 Antibody
TA392780FOXK1 Rabbit Polyclonal Antibody
APR21778N-01FOXK1 Rabbit pAb (APR21778N)
GTR18606660-01FOXK1/MNF Rabbit pAb
YLD3162-01Rabbit anti-FOXK1 Antibody
562929-01FOXK1
481276FOXK1 (Protein Foxk1 Ensembl ENSRNOP00000001466)

Popular Products