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Net rabbit pAb

CAT: 0855-ES5102-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES5102-02Size:100 µL
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Background
This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Description
This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
Product Name Alternative
ELK3; NET; SAP2; ETS domain-containing protein Elk-3; ETS-related protein ERP; ETS-related protein NET; Serum response factor accessory protein 2; SAP-2; SRF accessory protein 2
UniProt
P41970
Swiss Prot
P41970
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Elk3. AA range:323-372
Target
Net
Clonality
Polyclonal
Source
Rabbit
Applications
IF; ELISA
Concentration
1 mg/ml
Dilution
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus.
Other Product Names
ELK3; NET; SAP2; ETS domain-containing protein Elk-3; ETS-related protein ERP; ETS-related protein NET; Serum response factor accessory protein 2; SAP-2; SRF accessory protein 2
Gene ID (Human)
2004

UniProtKB · P41970

ETS domain-containing protein Elk-3

ELK3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P41970
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ELK3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R6S6, Q6FG57, Q6GU29, Q9UD17
Protein keywords

Molecular function

ActivatorDNA-bindingRepressor

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Biological process

TranscriptionTranscription regulation

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