COL7A1 rabbit pAb

CAT: 0855-ES4749-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES4749-01Size:50 µL
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Background
Collagen type VII alpha 1 chain (COL7A1) Homo sapiens This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008]
Description
Collagen type VII alpha 1 chain (COL7A1) Homo sapiens This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008],
Product Name Alternative
COL7A1; Collagen alpha-1 (VII) chain; Long-chain collagen; LC collagen
UniProt
Q02388
Swiss Prot
Q02388
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Collagen VII alpha1. AA range:1841-1890
Target
COL7A1
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Secreted, extracellular space, extracellular matrix, basement membrane.
Other Product Names
COL7A1; Collagen alpha-1 (VII) chain; Long-chain collagen; LC collagen
Gene ID (Human)
1294

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