Products for Research Use Only
RegisterLogin

A Cyclase VIII rabbit pAb

CAT: 0855-ES4642-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES4642-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq, Jul 2008]
Description
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq, Jul 2008],
Product Name Alternative
ADCY8; Adenylate cyclase type 8; ATP pyrophosphate-lyase 8; Adenylate cyclase type VIII; Adenylyl cyclase 8; AC8; Ca (2+) /calmodulin-activated adenylyl cyclase
UniProt
P40145
Swiss Prot
P40145
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human ADCY8. AA range:591-640
Target
A Cyclase VIII
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane . Apical cell membrane . Cell junction, synapse . Cell projection, dendrite . Cell projection, axon . Cell junction, synapse, presynaptic cell membrane . Cell junction, synapse, postsynaptic density . Membrane raft . Membrane, coated pit . Cytoplasmic vesicle, clathrin-coated vesicle membrane . Membrane, caveola . Localized to dendritic arbors (By similarity) . Monomeric N-glycosylated species localizes in membrane raft. In contrast, monomeric unglycosylated forms are enriched in clathrin-coated pits and vesicles. Dimers are also localized outside of membrane rafts. Membrane raft localization and integrity is indispensable for CCE-stimulated adenylate cyclase activity (By similarity) . .
Other Product Names
ADCY8; Adenylate cyclase type 8; ATP pyrophosphate-lyase 8; Adenylate cyclase type VIII; Adenylyl cyclase 8; AC8; Ca (2+) /calmodulin-activated adenylyl cyclase
Gene ID (Human)
114

Related Products

CatalogName
ES4635-01A Cyclase VII rabbit pAb
ES2314-01Factor VIII rabbit pAb
ES7546-01CA VIII rabbit pAb
ES5070-01A Cyclase IV rabbit pAb
ES1554-01A Cyclase I rabbit pAb
ES4651-01A Cyclase IX rabbit pAb
ES1555-01A Cyclase V/VI rabbit pAb
ES4608-01A Cyclase V/VI rabbit pAb
ES4103-01Annexin VII rabbit pAb
ES4666-01RAB3IP rabbit pAb

Alternative Products

CatalogName
GTR18051601-01A Cyclase VIII rabbit pAb Antibody
E28PT0035A Cyclase VIII Rabbit Polyclonal Antibody
PA88676HU-01Rabbit Anti-Human A Cyclase VIII Polyclonal Antibody
PAV4593Rabbit Anti-A Cyclase VIII/MOCS1 Polyclonal Antibody
C12038-01A Cyclase VIII Antibody
532573-01A Cyclase VIII discontinued
JOT-AP00057-01A Cyclase VIII Polyclonal Antibody
sc-40326-PRA cyclase VIII (m) -PR
sc-40325-PRA cyclase VIII (h) -PR
sc-40326A cyclase VIII siRNA (m)

Popular Products