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P23 (phospho Ser113) rabbit pAb

CAT: 0855-ES4544-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4544-01Size:50 µL
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Background
This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) . This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes. [provided by RefSeq, Feb 2016]
Description
This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes. [provided by RefSeq, Feb 2016],
UniProt
Q15185
Swiss Prot
Q15185
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human TEBP around the phosphorylation site of Ser113. AA range:79-128
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
24kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
24kD
Fragment
IgG
Subcellular Location
Cytoplasm .
Other Product Names
PTGES3; P23; TEBP; Prostaglandin E synthase 3; Cytosolic prostaglandin E2 synthase; cPGES; Hsp90 co-chaperone; Progesterone receptor complex p23; Telomerase-binding protein p23
Gene ID (Human)
10728

UniProtKB · Q15185

Prostaglandin E synthase 3

TEBP_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15185
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PTGES3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
5.3.99.3
Processing
—
Secondary accessions
A8K7D0, B4DHP2, B4DP11, B4DP21, Q8WU70
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Molecular function

ChaperoneIsomerase

Cellular component

Cytoplasm

Biological process

Fatty acid biosynthesisFatty acid metabolismLipid biosynthesisLipid metabolismProstaglandin biosynthesisProstaglandin metabolism

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