Vav3 rabbit pAb

• Background :

  This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

• Description :

  This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  VAV3; Guanine nucleotide exchange factor VAV3; VAV-3

• UniProt :

  Q9UKW4

• Swiss Prot :

  Q9UKW4

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human VAV3. AA range:139-188

• Target :

  Vav3

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  98kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  98kD

• Fragment :

  IgG

• Subcellular Location :

  Intracellular, cytosol, plasma membrane, extracellular exosome

• Other Product Names :

  VAV3; Guanine nucleotide exchange factor VAV3; VAV-3

• Gene ID (Human) :

  10451