GDF-3 rabbit pAb

• Background:

  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016]

• Description:

  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],

• UniProt:

  Q9NR23

• Swiss Prot:

  Q9NR23

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight:

  41kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  41kD

• Fragment:

  IgG

• Subcellular Location:

  Secreted . Cytoplasm . Mainly accumulated in the cytoplasm. .

• Other Product Names:

  GDF3; Growth/differentiation factor 3; GDF-3

• Gene ID (Human):

  9573