GDF-3 rabbit pAb

• Background :

  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016]

• Description :

  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],

• UniProt :

  Q9NR23

• Swiss Prot :

  Q9NR23

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight :

  41kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  41kD

• Fragment :

  IgG

• Subcellular Location :

  Secreted . Cytoplasm . Mainly accumulated in the cytoplasm. .

• Other Product Names :

  GDF3; Growth/differentiation factor 3; GDF-3

• Gene ID (Human) :

  9573