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BST-2 rabbit pAb

CAT: 0855-ES4342-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4342-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq, Jul 2008]
Description
Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq, Jul 2008],
Product Name Alternative
BST2; Bone marrow stromal antigen 2; BST-2; HM1.24 antigen; Tetherin; CD317
UniProt
Q10589
Swiss Prot
Q10589
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human BST2. AA range:101-150
Target
BST-2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
20kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
20kD
Fragment
IgG
Subcellular Location
Golgi apparatus, trans-Golgi network. Cell membrane ; Single-pass type II membrane protein. Cell membrane ; Lipid-anchor, GPI-anchor . Membrane raft. Cytoplasm. Apical cell membrane . Shuttles between the cell membrane, where it is present predominantly in membrane/lipid rafts, and the trans-Golgi network. Forms a complex with MMP14 and localizes to the cytoplasm.; Golgi apparatus, trans-Golgi network . Late endosome . (Microbial infection) HIV-1 VPU and HIV-2 ENV can target it to the trans-Golgi network thus sequestering it away from virus assembly sites on the cell membrane. Targeted to late endosomes upon KSHV infection and subsequent ubiquitination. .
Other Product Names
BST2; Bone marrow stromal antigen 2; BST-2; HM1.24 antigen; Tetherin; CD317
Gene ID (Human)
684

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