CD53 rabbit pAb

CAT: 0855-ES4321-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES4321-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Description
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Product Name Alternative
CD53; MOX44; TSPAN25; Leukocyte surface antigen CD53; Cell surface glycoprotein CD53; Tetraspanin-25; Tspan-25; CD53
UniProt
P19397
Swiss Prot
P19397
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CD53. AA range:91-140
Target
CD53
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
24kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
24kD
Fragment
IgG
Subcellular Location
Cell membrane . Cell junction . Membrane; Multi-pass membrane protein. Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes. .
Other Product Names
CD53; MOX44; TSPAN25; Leukocyte surface antigen CD53; Cell surface glycoprotein CD53; Tetraspanin-25; Tspan-25; CD53
Gene ID (Human)
963

Related Products

CatalogName
ES3980-01CD55 rabbit pAb
ES3981-01CD58 rabbit pAb
ES8787-01CD52 rabbit pAb
ES3982-01CD59 rabbit pAb
ES5811-01CD50 rabbit pAb
ES8423-01CD56 rabbit pAb
ES5540-01CD57 rabbit pAb
ES10519-01CD5L rabbit pAb
ES1912-01CD5 rabbit pAb
ES5810-01CD50 (phospho Ser518) rabbit pAb

Alternative Products

CatalogName
MBS8540503-01CD53 Rabbit pAb
E60M3044CD53 Rabbit mAb
MBS9148118-01CD53 Rabbit PolymAb
APRab08416-01CD53 Rabbit Polyclonal Antibody
A04993-100CD53 Antibody, mAb, Rabbit
YLD1592-01Rabbit anti-CD53 Antibody
NBP2-14464Rabbit Polyclonal CD53 Antibody
E56G2711CD53 Rabbit Monoclonal Antibody

Popular Products