Products for Research Use Only
RegisterLogin

Syntaxin 1 rabbit pAb

CAT: 0855-ES4170-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES4170-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein) -Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc) . Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Description
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],
Product Name Alternative
STX1A; STX1; Syntaxin-1A; Neuron-specific antigen HPC-1
UniProt
Q16623
Swiss Prot
Q16623
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human STX1A. AA range:31-80
Target
Syntaxin 1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
30kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
30kD
Fragment
IgG
Subcellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type IV membrane protein . Cell junction, synapse, synaptosome . Cell membrane . Colocalizes with KCNB1 at the cell membrane. .; [Isoform 2]: Secreted .
Other Product Names
STX1A; STX1; Syntaxin-1A; Neuron-specific antigen HPC-1
Gene ID (Human)
6804

Related Products

CatalogName
ES7314-01Syntaxin 1 (phospho Ser14) rabbit pAb
ES20386-01Syntenin rabbit pAb
ES4354-01SIRP-α1/β1 rabbit pAb
ES20692-01Kininogen 1 Rabbit rabbit pAb
EA313-01Kv11.1 Rabbit pAb
ES1718-01Ataxin-1 rabbit pAb
ES1577-01ACAT-1 rabbit pAb
ES4382-01IRF-1 rabbit pAb
ES4055-01EPAS-1 rabbit pAb
ES1599-01ADAMTS-1 rabbit pAb

Alternative Products

CatalogName
E47R20574Syntaxin 1A + Syntaxin 1B Rabbit pAb
56510Syntaxin Rabbit mAb
APA2625-01Syntaxin Rabbit pAb
TA308160Rabbit Polyclonal antibody to Syntaxin 5 (syntaxin 5)
GTR17711014-01Syntaxin 1A + Syntaxin 1B Rabbit Polyclonal Antibody
SL20574R-01Rabbit Anti-Syntaxin 1A + Syntaxin 1B antibody
E28PN8722Syntaxin 1A/Syntaxin 1B Rabbit Polyclonal Antibody
GTR17850842Syntaxin 1A + Syntaxin 1B Rabbit Polyclonal Antibody (RBITC)
GTR18462681Syntaxin 1A + Syntaxin 1B Rabbit Polyclonal Antibody (BF405)
GTR18462679Syntaxin 1A + Syntaxin 1B Rabbit Polyclonal Antibody (BF488)

Popular Products