Products for Research Use Only
RegisterLogin

Gp91-phox rabbit pAb

CAT: 0855-ES4113-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES4113-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD) . In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
Description
Cytochrome b (-245) is composed of Cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008],
Product Name Alternative
CYBB; NOX2; Cytochrome b-245 heavy chain; CGD91-phox; Cytochrome b (558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; gp91-1; gp91-phox; p22 phagocyte B-cytochrome
UniProt
P04839
Swiss Prot
P04839
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CYBB. AA range:111-160
Target
Gp91-phox
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
70kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
70kD
Fragment
IgG
Subcellular Location
Cell membrane; Multi-pass membrane protein. As unassembled monomer may localize to the endoplasmic reticulum. .
Other Product Names
CYBB; NOX2; Cytochrome b-245 heavy chain; CGD91-phox; Cytochrome b (558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; gp91-1; gp91-phox; p22 phagocyte B-cytochrome
Gene ID (Human)
1536

Related Products

CatalogName
ES2443-01gp91-phox Rabbit Polyclonal Antibody
ES3115-01P47-phox rabbit pAb
ES7224-01P47-phox (phospho Ser370) rabbit pAb
ES6339-01P40-phox (phospho Thr154) rabbit pAb
ES7221-01P47-phox (phospho Ser345) rabbit pAb
ES7223-01P47-phox (phospho Ser328) rabbit pAb
ES7220-01P47-phox (phospho Ser304) rabbit pAb
ES7222-01P47-phox (phospho Ser359) rabbit pAb
ES3114-01p47-phox Rabbit Polyclonal Antibody
ES6340-01p40-phox Rabbit Polyclonal Antibody

Alternative Products

CatalogName
MBS8539974-01GP91-phox Rabbit pAb
GTR18051466Gp91-phox rabbit pAb Antibody
E2251327Gp91-phox/NOX2 Rabbit pAb
DL90306A-01Rabbit anti-gp91 phox Antibody
GTR18103694-01Gp91 phox Rabbit Polyclonal Antibody
E28PT5383Gp91-phox Rabbit Polyclonal Antibody
CMA5447-01Recombinant Anti-gp91 phox Rabbit mAb
PA84347HU-01Rabbit Anti-Human gp91-phox Polyclonal Antibody
PAV7624Rabbit Anti-gp91-phox/CYBB Polyclonal Antibody
MBS4753383-01p40-phox Rabbit mAb

Popular Products