Annexin VII rabbit pAb

CAT: 0855-ES4103-01Size: 50 µLDry Ice: NoHazardous: No

1 / 1

CAT#:0855-ES4103-01Size:50 µL

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Background

Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly (A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the

Description

Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins. The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2. 0 and 2. 4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly (A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the

UniProt

P20073

Swiss Prot

P20073

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human ANXA7. AA range:271-320

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

53kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

53kD

Fragment

IgG

Subcellular Location

Nucleus, nuclear envelope, endoplasmic reticulum membrane, cytosol, plasma membrane, membrane, chromaffin granule membrane, extracellular exosome

Other Product Names

ANXA7; ANX7; SNX; OK/SW-cl.95; Annexin A7; Annexin VII; Annexin-7; Synexin

Gene ID (Human)

310

UniProtKB · P20073

Annexin A7

ANXA7_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P20073
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: ANXA7
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: Q5F2H3, Q5T0M6, Q5T0M7

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Acetylation

Coding sequence diversity

Alternative splicing

Domain

AnnexinRepeat

Ligand

CalciumCalcium/phospholipid-binding

Related Products

Catalog	Name
ES4635-01	A Cyclase VII rabbit pAb
ES5712-01	Annexin I rabbit pAb
ES1658-01	Annexin VI rabbit pAb
ES1659-01	Annexin X rabbit pAb
ES8636-01	Annexin I rabbit pAb
ES1657-01	Annexin III rabbit pAb
ES1656-01	Annexin II rabbit pAb
ES7123-01	Na+ CP type VIIα rabbit pAb
ES1058-01	Cleaved-Factor VII LC (R212) rabbit pAb
ES1534-01	Annexin I (phospho Tyr21) rabbit pAb

Alternative Products

Catalog	Name
MBS8575786-01	Annexin VI/Annexin A6 Rabbit pAb
A6280-01	Annexin A4/Annexin IV Rabbit pAb
A9203-01	Annexin A4/Annexin IV Rabbit mAb
E45R12113N	Annexin A5/Annexin V Rabbit mAb
A5390-01	Annexin A6/Annexin VI Rabbit pAb
E45R20506N	Annexin A5/Annexin V Rabbit pAb
A22038-01	Annexin A6/Annexin VI Rabbit mAb
APR26388N-01	Annexin A4/Annexin IV Rabbit pAb (APR26388N)
MBS2602495-01	Rabbit Annexin A5 (Annexin A5) ELISA Kit
APR20506N-01	Annexin A5/Annexin V Rabbit pAb (APR20506N)