Macroglobulin α-2 rabbit pAb

• Background:

  Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq, Jul 2008]

• Description:

  Alpha-2-macroglobulin is a protease inhibitor and Cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq, Jul 2008],

• UniProt:

  P01023

• Swiss Prot:

  P01023

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from the Internal region of human A2M. AA range:871-920

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  170kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  170kD

• Fragment:

  IgG

• Subcellular Location:

  Secreted .

• Other Product Names:

  A2M; CPAMD5; FWP007; Alpha-2-macroglobulin; Alpha-2-M; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5

• Gene ID (Human):

  2