SCCA1/2 rabbit pAb

• Background:

  Developmental stage:Its expression is closely related to cellular differentiation in both normal and malignant squamous cells., function:May act as a protease inhibitor to modulate the host immune response against tumor cells., similarity:Belongs to the serpin family., similarity:Belongs to the serpin family. Ov-serpin subfamily., subcellular location:Seems to also be secreted in plasma by cancerous cells but at a low level., tissue specificity:Squamous cells. Expressed in some hepatocellular carcinoma (at protein level) .

• Description:

  Developmental stage: Its expression is closely related to cellular differentiation in both normal and malignant squamous cells. function: May act as a protease inhibitor to modulate the host immune response against tumor cells. similarity: Belongs to the serpin family. similarity: Belongs to the serpin family. Ov-serpin subfamily. subcellular location: Seems to also be secreted in plasma by cancerous cells but at a low level. tissue specificity: Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).

• Synonyms:

  SERPINB3; SCCA; SCCA1; Serpin B3; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1

• Gene ID:

  6317

• UniProt:

  P29508

• Cellular Locus:

  Cytoplasm. Seems to also be secreted in plasma by cancerous cells but at a low level.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse,

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from the Internal region of human SERPINB3/4. AA range:111-160

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC, IF, ELISA

• Validated Applications:

  WB, IHC, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  45kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  45 kD

• Subcellular Location:

  Cytoplasm . Seems to also be secreted in plasma by cancerous cells but at a low level.

• Other Product Names:

  SERPINB3; SCCA; SCCA1; Serpin B3; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1

• Gene ID (Human):

  6317

• SwissProt (Human):

  P29508