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Siglec-5/14 rabbit pAb

CAT:
855-ES4000-02
Size:
100 μL
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
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Siglec-5/14 rabbit pAb

  • Description: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012],
  • Synonyms: SIGLEC5; CD33L2; OBBP2; Sialic acid-binding Ig-like lectin 5; Siglec-5; CD33 antigen-like 2; Obesity-binding protein 2; OB-BP2; OB-binding protein 2; CD170; SIGLEC14; Sialic acid-binding Ig-like lectin 14; Siglec-14
  • Gene ID: 8778
  • UniProt: O15389
  • Cellular Locus: Membrane; Single-pass type I membrane protein.
  • Host: Rabbit
  • Species Reactivity: Human, Rat, Mouse,
  • Immunogen: Synthesized peptide derived from Sialic acid-binding Ig-like lectin 5/Sialic acid-binding Ig-like lectin 14 at AA range: 91-140
  • Clonality: Polyclonal
  • Validated Applications: WB, IHC, IF, ELISA
  • Stability: 1 year
  • Concentration: 1 mg/mL
  • Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
  • Molecular Weight: 60kD
  • Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Datasheet