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ADM rabbit pAb

CAT: 0855-ES3932-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3932-02Size:100 µL
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Background
The protein encoded by this gene is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E. coli and S. aureus at low concentration. [provided by RefSeq, Aug 2014]
Description
The protein encoded by this gene is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E. coli and S. aureus at low concentration. [provided by RefSeq, Aug 2014],
Product Name Alternative
ADM; AM; ADM
UniProt
P35318
Swiss Prot
P35318
Reactivity
Human; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human ADM. AA range:101-150
Target
ADM
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
20kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
20kD
Fragment
IgG
Subcellular Location
Secreted.
Other Product Names
ADM; AM; ADM
Gene ID (Human)
133

UniProtKB · P35318

Pro-adrenomedullin

ADML_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35318
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ADM
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2R793, D3DQV3, Q6FGW2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AmidationCleavage on pair of basic residuesDisulfide bond

Molecular function

Hormone

Cellular component

Secreted

Domain

Signal

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