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IL-31Rα rabbit pAb

CAT: 0855-ES3821-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3821-01Size:50 µL
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Background
The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR) . Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]
Description
The protein encoded by this gene belongs to the type I Cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jun 2011],
Product Name Alternative
IL31RA; CRL3; GPL; Interleukin-31 receptor subunit alpha; IL-31 receptor subunit alpha; IL-31R subunit alpha; IL-31R-alpha; IL-31RA; Cytokine receptor-like 3; GLM-R; hGLM-R; Gp130-like monocyte receptor; Gp130-like receptor; ZcytoR17
UniProt
Q8NI17
Swiss Prot
Q8NI17
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from the Internal region of human IL-31Rα.
Target
IL-31Rα
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
82kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
82kD
Fragment
IgG
Subcellular Location
Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse, presynaptic cell membrane . Cell projection, axon .
Other Product Names
IL31RA; CRL3; GPL; Interleukin-31 receptor subunit alpha; IL-31 receptor subunit alpha; IL-31R subunit alpha; IL-31R-alpha; IL-31RA; Cytokine receptor-like 3; GLM-R; hGLM-R; Gp130-like monocyte receptor; Gp130-like receptor; ZcytoR17
Gene ID (Human)
133396

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