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Stathmin-2 rabbit pAb

CAT: 0855-ES3806-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3806-01Size:50 µL
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Background
This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010]
Description
This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010],
Product Name Alternative
STMN2; SCG10; SCGN10; Stathmin-2; Superior cervical ganglion-10 protein; Protein SCG10
UniProt
Q93045
Swiss Prot
Q93045
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the Internal region of human Stathmin-2.
Target
Stathmin-2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
20kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
20kD
Fragment
IgG
Subcellular Location
Cytoplasm . Cytoplasm, perinuclear region . Cell projection, growth cone. Membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, axon. Golgi apparatus. Endosome . Cell projection, lamellipodium. Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane-bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons (By similarity) . Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamellipodia. .
Other Product Names
STMN2; SCG10; SCGN10; Stathmin-2; Superior cervical ganglion-10 protein; Protein SCG10
Gene ID (Human)
11075

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