QP5038

• Description :

  QP5038 (compound 28) is an inhibitor of QPCTL with an IC50 value of 3.8 nM. QP5038 has antitumor efficacy[1].

• CAS Number :

  [3031429-88-3]

• UNSPSC :

  12352005

• Target :

  Amyloid-β

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/qp5038.html

• Purity :

  99.51

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  N#CC1=CC=CC(C2=CC=C(F)N=C2)=C1N3CCC(C4=CN=CN4C)CC3

• Molecular Formula :

  C21H20FN5

• Molecular Weight :

  361.42

• References & Citations :

  [1]Lei Yu, et al. Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy. Signal Transduct Target Ther. 2023, 8, 1.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported