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Somatostatin rabbit pAb

CAT: 0855-ES3479-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3479-01Size:50 µL
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Background
The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]
Description
The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008],
UniProt
P61278
Swiss Prot
P61278
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Somatostatin. AA range:10-59
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
17kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
17kD
Fragment
IgG
Subcellular Location
Secreted .
Other Product Names
SST; Somatostatin; Growth hormone release-inhibiting factor
Gene ID (Human)
6750

UniProtKB · P61278

Somatostatin

SMS_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P61278
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SST
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2R5G3, P01166
Protein keywords

Technical term

3D-structurePharmaceuticalProteomics identificationReference proteome

PTM

AmidationCleavage on pair of basic residuesDisulfide bond

Molecular function

Hormone

Cellular component

Secreted

Domain

Signal

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