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PKA Iβ reg rabbit pAb

CAT: 0855-ES3219-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3219-01Size:50 µL
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Background
The protein encoded by this gene is a regulatory subunit of cyclic AMP-dependent protein kinase A (PKA), which is involved in the signaling pathway of the second messenger cAMP. Two regulatory and two catalytic subunits form the PKA holoenzyme, disbands after cAMP binding. The holoenzyme is involved in many cellular events, including ion transport, metabolism, and transcription. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2015]
Description
The protein encoded by this gene is a regulatory subunit of cyclic AMP-dependent protein kinase A (PKA), which is involved in the signaling pathway of the second messenger cAMP. Two regulatory and two catalytic subunits form the PKA holoenzyme, disbands after cAMP binding. The holoenzyme is involved in many cellular events, including ion transport, metabolism, and transcription. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2015],
UniProt
P31321
Swiss Prot
P31321
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human KAP1. AA range:106-155
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
43kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
43kD
Fragment
IgG
Subcellular Location
Cell membrane .
Other Product Names
PRKAR1B; cAMP-dependent protein kinase type I-beta regulatory subunit
Gene ID (Human)
5575

UniProtKB · P31321

cAMP-dependent protein kinase type I-beta regulatory subunit

KAP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P31321
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRKAR1B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q8N422
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

cAMPcAMP-bindingNucleotide-binding

Cellular component

Cell membraneMembrane

Disease

Disease variantIntellectual disability

PTM

Disulfide bondMethylationNitrationPhosphoprotein

Domain

Repeat