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P130 Cas rabbit pAb

CAT: 0855-ES3094-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3094-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al., 2006 [PubMed 17129785]) .[supplied by OMIM, May 2009]
Description
BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al. 2006 [PubMed 17129785]). [supplied by OMIM, May 2009],
Product Name Alternative
BCAR1; CAS; CASS1; CRKAS; Breast cancer anti-estrogen resistance protein 1; CRK-associated substrate; Cas scaffolding protein family member 1; p130cas
UniProt
P56945
Swiss Prot
P56945
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human p130 Cas. AA range:376-425
Target
P130 Cas
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
130kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
130kD
Fragment
IgG
Subcellular Location
Cell junction, focal adhesion . Cytoplasm . Cell projection, axon . Unphosphorylated form localizes in the cytoplasm (By similarity) . Localizes to focal adhesion sites following integrin engagement (By similarity) . .
Other Product Names
BCAR1; CAS; CASS1; CRKAS; Breast cancer anti-estrogen resistance protein 1; CRK-associated substrate; Cas scaffolding protein family member 1; p130cas
Gene ID (Human)
9564

UniProtKB · P56945

Breast cancer anti-estrogen resistance protein 1

BCAR1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P56945
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BCAR1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B3KWD7, B4DEV4, B4DGB5, B4DIW5, B7Z7X7, E9PCL5, E9PCV2, F5GXA2, F5GXV6, F5H7Z0, F8WA69, Q6QEF7
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesion

Cellular component

Cell junctionCell projectionCytoplasm

Disease

Diabetes mellitus

Domain

SH3 domainSH3-binding

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