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Olfactory receptor 4K14 rabbit pAb

CAT: 0855-ES3043-01Size: 50 µLDry Ice: NoHazardous: No
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Background
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Description
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008],
Product Name Alternative
OR4K14; Olfactory receptor 4K14; Olfactory receptor OR14-22
UniProt
Q8NGD5
Swiss Prot
Q8NGD5
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human OR4K14. AA range:261-310
Target
Olfactory receptor 4K14
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
35kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
35kD
Fragment
IgG
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Other Product Names
OR4K14; Olfactory receptor 4K14; Olfactory receptor OR14-22
Gene ID (Human)
122740

UniProtKB · Q8NGD5

Olfactory receptor 4K14

OR4KE_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8NGD5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
OR4K14
Protein existence
3: Inferred from homology
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q6IEU1, Q96R71
Protein keywords

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoprotein

Molecular function

G protein-coupled receptorReceptorTransducer

Biological process

OlfactionSensory transduction

Technical term

Reference proteome

Domain

TransmembraneTransmembrane helix

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