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Na+ CP type IXα rabbit pAb

CAT: 0855-ES2890-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2890-01Size:50 µL
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Background
This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq, Aug 2009]
Description
This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq, Aug 2009],
UniProt
Q15858
Swiss Prot
Q15858
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human SCN9A. AA range:651-700
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
220kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
220kD
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein . Cell projection, neuron projection . In neurite terminals. .
Other Product Names
SCN9A; NENA; Sodium channel protein type 9 subunit alpha; Neuroendocrine sodium channel; hNE-Na; Peripheral sodium channel 1; PN1; Sodium channel protein type IX subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.7
Gene ID (Human)
6335

UniProtKB · Q15858

Sodium channel protein type 9 subunit alpha

SCN9A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15858
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SCN9A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A1BUH5, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCell projectionMembrane

Disease

Disease variantEpilepsy

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation

Molecular function

Ion channelSodium channelVoltage-gated channel

Biological process

Ion transportSodium transportTransport

Domain

RepeatTransmembraneTransmembrane helix

Ligand

Sodium

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