Products for Research Use Only
RegisterLogin

MGluR-7 rabbit pAb

CAT: 0855-ES2787-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES2787-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Glutamate metabotropic receptor 7 (GRM7) Homo sapiens L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found
Description
Glutamate metabotropic receptor 7 (GRM7) Homo sapiens L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found
UniProt
Q14831
Swiss Prot
Q14831
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human mGluR7. AA range:866-915
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
100kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
100kD
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein .
Other Product Names
GRM7; GPRC1G; MGLUR7; Metabotropic glutamate receptor 7; mGluR7
Gene ID (Human)
2917

Related Products

CatalogName
ES5680-01MGluR-8 rabbit pAb
ES2785-01MGluR-4 rabbit pAb
ES5678-01MGluR-6 rabbit pAb
ES5675-01MGluR-2/3 rabbit pAb
ES1993-01CLC-7 rabbit pAb
ES4141-01MDA-7 rabbit pAb
ES4379-01GDF-7 rabbit pAb
ES4711-01CKR-7 rabbit pAb
ES4793-01Claudin-7 rabbit pAb
ES1826-01Cadherin-7 rabbit pAb

Alternative Products

CatalogName
E28PT2747MgluR-7 Rabbit Polyclonal Antibody
PAV8903Rabbit Anti-mGluR-7/GRM7 Polyclonal Antibody
PA84454HU-01Rabbit Anti-Human mGluR-7 Polyclonal Antibody
APRab13861-01MGluR-4 Rabbit Polyclonal Antibody
E28PT2746MgluR-6 Rabbit Polyclonal Antibody
APRab13866-01MGluR-8 Rabbit Polyclonal Antibody
BS9933MmGluR-5 Rabbit monoclonal antibody
E28PT2743MgluR-2/3 Rabbit Polyclonal Antibody
PAV8899Rabbit Anti-mGluR-4/GRM4 Polyclonal Antibody
PA89289HU-01Rabbit Anti-Human mGluR-8 Polyclonal Antibody

Popular Products