Galectin-9 rabbit pAb

• Background:

  The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

• Description:

  The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008],

• Synonyms:

  LGALS9; Galectin-9; Gal-9; Ecalectin; Tumor antigen HOM-HD-21

• Gene ID:

  3965

• UniProt:

  O00182

• Cellular Locus:

  Cytoplasm. Nucleus. Secreted. May also be secreted by a non-classical secretory pathway (By similarity). Secreted by mesenchymal stromal cells upon IFNG stimulation (PubMed:23817958)..; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human LEG9. AA range:51-100

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC, IF, ELISA

• Validated Applications:

  WB, IHC, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight:

  40kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  40 kD

• Subcellular Location:

  Cytoplasm . Nucleus . Secreted . May also be secreted by a non-classical secretory pathway (By similarity) . Secreted by mesenchymal stromal cells upon IFNG stimulation (PubMed:23817958) . .; [Isoform 2]: Secreted .; [Isoform 3]: Secreted .

• Other Product Names:

  LGALS9; Galectin-9; Gal-9; Ecalectin; Tumor antigen HOM-HD-21

• Gene ID (Human):

  3965

• SwissProt (Human):

  O00182