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Fra-1 rabbit pAb

CAT: 0855-ES2370-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2370-01Size:50 µL
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Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Description
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
UniProt
P15407
Swiss Prot
P15407
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Fra-1. AA range:101-150
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
43kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
43kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
FOSL1; FRA1; Fos-related antigen 1; FRA-1
Gene ID (Human)
8061

UniProtKB · P15407

Fos-related antigen 1

FOSL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P15407
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FOSL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
FRA-1
EC number
—
Processing
—
Secondary accessions
B4DR11, Q6FG51
Protein keywords

Coding sequence diversity

Alternative splicing

Molecular function

DNA-binding

Cellular component

Nucleus

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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