Products for Research Use Only
RegisterLogin

Ezrin rabbit pAb

CAT: 0855-ES2313-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES2313-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]
Description
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008],
UniProt
P15311
Swiss Prot
P15311
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Ezrin. AA range:511-560
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
70kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
70kD
Fragment
IgG
Subcellular Location
Apical cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection . Cell projection, microvillus membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Cell projection, microvillus . Localization to the apical membrane of parietal cells depends on the interaction with PALS1. Localizes to cell extensions and peripheral processes of astrocytes (By similarity) . Microvillar peripheral membrane protein (cytoplasmic side) . .
Other Product Names
EZR; VIL2; Ezrin; Cytovillin; Villin-2; p81
Gene ID (Human)
7430

Related Products

CatalogName
ES7501-01Ezrin (phospho Tyr353) rabbit pAb
ES7502-01Ezrin (phospho Tyr146) rabbit pAb
ES7503-01Ezrin (phospho Tyr478) rabbit pAb
ES7500-01Ezrin (phospho Thr566) rabbit pAb
ES6284-01Moesin/Ezrin/Radixin rabbit pAb
ES6283-01Moesin/Ezrin/Radixin (phospho Thr558) rabbit pAb
ES2311-01Ezrin Rabbit Polyclonal Antibody
ES7504-01Ezrin Rabbit Polyclonal Antibody
ES2312-01Ezrin Rabbit Polyclonal Antibody
ES2310-01Ezrin Rabbit Polyclonal Antibody

Alternative Products

CatalogName
MBS4753264-01Ezrin Rabbit mAb
E45R17529N-50Ezrin Rabbit pAb

Popular Products