EphB6 rabbit pAb

CAT: 0855-ES2274-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES2274-01Size:50 µL
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Background
This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Description
This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Product Name Alternative
EPHB6; Ephrin type-B receptor 6; HEP; Tyrosine-protein kinase-defective receptor EPH-6
UniProt
O15197
Swiss Prot
O15197
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human EPHB6. AA range:861-910
Target
EphB6
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
119kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
119kD
Fragment
IgG
Subcellular Location
Membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted .
Other Product Names
EPHB6; Ephrin type-B receptor 6; HEP; Tyrosine-protein kinase-defective receptor EPH-6
Gene ID (Human)
2051

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