ENX-2 rabbit pAb

• Background :

  Enhancer of zeste 1 polycomb repressive complex 2 subunit (EZH1) Homo sapiens EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]) .[supplied by OMIM, Mar 2009]

• Description :

  Enhancer of zeste 1 polycomb repressive complex 2 subunit (EZH1) Homo sapiens EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al. 2008 [PubMed 19026780]). [supplied by OMIM, Mar 2009],

• UniProt :

  Q92800

• Swiss Prot :

  Q92800

• Reactivity :

  Human; Mouse; Monkey

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human EZH1. AA range:171-220

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight :

  85kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  85kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus . Colocalizes with trimethylated 'Lys-27' of histone H3.

• Other Product Names :

  EZH1; KIAA0388; Histone-lysine N-methyltransferase EZH1; ENX-2; Enhancer of zeste homolog 1

• Gene ID (Human) :

  2145