Casein Kinase IIβ rabbit pAb

• Background:

  This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

• Description:

  This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013],

• Synonyms:

  CSNK2B; CK2N; G5A; Casein kinase II subunit beta; CK II beta; Phosvitin; Protein G5a

• Gene ID:

  1460

• UniProt:

  P67870

• Cellular Locus:

  Nucleus,nucleoplasm,cytoplasm,cytosol,plasma membrane,protein kinase CK2 complex,PcG protein complex,extracellular exosome,

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human CKII-beta. AA range:166-215

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC, IF, ELISA

• Validated Applications:

  WB, IHC, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

• Molecular Weight:

  25kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  25 kD

• Subcellular Location:

  Nucleus, nucleoplasm, cytoplasm, cytosol, plasma membrane, protein kinase CK2 complex, PcG protein complex, extracellular exosome

• Other Product Names:

  CSNK2B; CK2N; G5A; Casein kinase II subunit beta; CK II beta; Phosvitin; Protein G5a

• Gene ID (Human):

  1460

• SwissProt (Human):

  P67870