AP-2α/β rabbit pAb

CAT: 0855-ES1670-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES1670-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transcription factor AP-2 alpha (TFAP2A) Homo sapiens The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS) . Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]
Description
Transcription factor AP-2 alpha (TFAP2A) Homo sapiens The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009],
UniProt
P05549/Q92481
Swiss Prot
P05549/Q92481
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human AP-2. AA range:388-437
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
49kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
49kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
TFAP2A; AP2TF; TFAP2; Transcription factor AP-2-alpha; AP2-alpha; AP-2 transcription factor; Activating enhancer-binding protein 2-alpha; Activator protein 2; AP-2; TFAP2B; Transcription factor AP-2-beta; AP2-beta; Activating enhancer-bindi
Gene ID (Human)
7020

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