JAK1 (phospho Tyr1022) rabbit pAb

CAT:

855-ES1347-01

Size:

50 μL

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Description: This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Synonyms: JAK1; JAK1A; JAK1B; Tyrosine-protein kinase JAK1; Janus kinase 1; JAK-1
Gene ID: 3716
UniProt: P23458
Cellular Locus: Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: The antiserum was produced against synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022. AA range:988-1037
Clonality: Polyclonal
Validated Applications: IF, WB, IP, IHC, ELISA
Stability: 1 year
Concentration: 1 mg/mL
Dilution: IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight: 132kD
Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.