Cytokeratin 8 (phospho Ser73) rabbit pAb
CAT:
855-ES1296-02
Size:
100 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Cytokeratin 8 (phospho Ser73) rabbit pAb
- Description: Keratin 8 (KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
- Synonyms: KRT8; CYK8; Keratin; type II cytoskeletal 8; Cytokeratin-8; CK-8; Keratin-8; K8; Type-II keratin Kb8
- Gene ID: 3856
- UniProt: P05787
- Cellular Locus: Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.
- Host: Rabbit
- Species Reactivity: Human, Mouse
- Immunogen: The antiserum was produced against synthesized peptide derived from human Keratin 8 around the phosphorylation site of Ser73. AA range:41-90
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
- Molecular Weight: 55kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.