α-actinin Rabbit pAb

• Background :

  α-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.

• Description :

  α-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.

• UniProt :

  P12814

• Swiss Prot :

  P12814

• Reactivity :

  Rat, Mouse

• Immunogen :

  Recombinant Protein

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB, IHC

• Concentration :

  1mg/mL

• Dilution :

  WB 1:1,000-2,000 IHC 1:200-500

• Molecular Weight :

  103kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight :

  103kDa

• Fragment :

  IgG

• Subcellular Location :

  Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane

• Other Product Names :

  Actinin 1 smooth muscle antibody, actinin alpha 1 antibody, ACTN 1 antibody, FLJ40884 antibody

• Gene ID (Human) :

  87