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PI3 Kinase P85α Rabbit pAb

CAT: 0855-EA199-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-EA199-01Size:50 µL
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Background
Phosphatidylinositol-4,5-bisphosphate 3-kinase (also called phosphatidylinositide 3-kinases, phosphatidylinositol-3-kinases, PI 3-kinases, PI (3) Ks, PI-3Ks or by the HUGO official stem symbol for the gene family, PI3K (s) ) are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.
Description
Phosphatidylinositol-4, 5-bisphosphate 3-kinase (also called phosphatidylinositide 3-kinases, phosphatidylinositol-3-kinases, PI 3-kinases, PI (3)Ks, PI-3Ks or by the HUGO official stem symbol for the gene family, PI3K (s)) are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.
Product Name Alternative
GRB1 antibody, p85 alpha antibody, PI3K antibody, PIK3R1 antibody
UniProt
P27986
Swiss Prot
P27986
Reactivity
Rat, Mouse
Immunogen
Recombinant Protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1mg/mL
Dilution
WB 1:1,000-2,000
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
85kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
85kDa
Fragment
IgG
Subcellular Location
Cytosol, Endoplasmic reticulum, Golgi apparatus, Nucleus, Plasma Membrane
Other Product Names
GRB1 antibody, p85 alpha antibody, PI3K antibody, PIK3R1 antibody
Gene ID (Human)
5295

UniProtKB · P27986

Phosphatidylinositol 3-kinase regulatory subunit alpha

P85A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P27986
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PIK3R1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha
EC number
—
Processing
—
Secondary accessions
B3KT19, D3DWA0, E7EX19, Q15747, Q4VBZ7, Q53EM6, Q8IXA2, Q8N1C5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasm

Disease

Disease variantDwarfism

Molecular function

GTPase activation

Biological process

Host-virus interactionProtein transportStress responseTransport

Domain

RepeatSH2 domainSH3 domain

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RA20265-01PI3 Kinase P85 Rabbit Polyclonal Antibody(PI3K p85)
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