Active Caspase 3 Mouse mAb

• Background:

  Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position.

• Description:

  Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position.

• UniProt:

  P42574

• Swiss Prot:

  P42574

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Recombinant Protein

• Clonality:

  Monoclonal

• Source:

  Mouse

• Applications:

  WB, IHC

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1,000 IHC 1:100-200

• Molecular Weight:

  17kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  17kDa

• Fragment:

  IgG1

• Subcellular Location:

  Cytoplasm

• Other Product Names:

  APOPAIN antibody, CASP 3 antibody, CPP32 antibody, Cysterine protease CPP32 antibody

• Gene ID (Human):

  836