Boc-Val-Leu-Lys-AMC

• UNSPSC Description:

  Boc-Val-Leu-Lys-AMC is a sensitive, fluorogenic, and specific substrate of plasmin, as well as acrosin from the ascidian Halocynthia roretzi, porcine calpain isozymes I and II, and papain[1][2][3][4].

• Target Antigen:

  Others

• Type:

  Peptides

• Related Pathways:

  Others

• Field of Research:

  others

• Assay Protocol:

  https://www.medchemexpress.com/boc-val-leu-lys-amc.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C1=CC=C(NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC(OC(C)(C)C)=O)=O)=O)=O)C=C1O2)=CC2=O

• Molecular Weight:

  615.76

• References & Citations:

  [1]T Sasaki, et al. Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates. J Biol Chem. 1984 Oct 25;259(20):12489-94.|[2]H Kato, et al. New fluorogenic peptide substrates for plasmin. J Biochem. 1980 Jul;88(1):183-90.|[3]R E Smith, et al. Direct photometric or fluorometric assay of proteinases using substrates containing 7-amino-4-trifluoromethylcoumarin. Thromb Res. 1980 Feb;17(3-4):393-402.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  73554-84-4