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R112

CAT: 0026-B2913-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B2913-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
R112 is an inhibitor of spleen tyrosine kinase (Syk) with an IC₅₀ of 226 nM in cultured human mast cells. It is an ATP-competitive Syk inhibitor with a Ki of 96 nM. It completely and rapidly inhibits all mast cell activation cascades triggered by IgE receptor cross-linking: degranulation, lipid mediator production, and cytokine production.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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