Products for Research Use Only
RegisterLogin

NSC109116

CAT: 0026-B2911-1Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0026-B2911-1Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NSC109116 is an inhibitor of human 20α-hydroxysteroid dehydrogenase (AKR1C1), an aldo-keto reductase (AKR) enzyme. AKR1C1 metabolizes progesterone to an inactive form, 20α-hydroxy progesterone. NSC109116 is a salicylic compound that selectively inhibits AKR1C1 (Ki = 4 nM) over AKR1C2. It potently inhibits the metabolism of progesterone in bovine aortic endothelial cells overexpressing AKR1C1 with an IC₅₀ of 460 nM.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

Popular Products