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WHI-P180

CAT: 26-B2908-25Size: 25 mgDry Ice: NoHazardous: No
25 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WHI-P180 is a multi-kinase inhibitor. It inhibits human proto-oncogene receptor tyrosine kinase RET (Rearranged during Transfection) and kinase insert domain receptor (KDR) with IC₅₀ values of 4.5 nM and 66 nM respectively. It inhibits epidermal growth factor receptor (EGFR) kinase with an IC₅₀ of 4.0 μM and also inhibits Janus kinase 3 (JAK3). It exhibits potent anti-graft-versus-host disease activity and IgE-mediated mast cell responses in vitro and in vivo.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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