Sempervirine

• Description :

  Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC50 values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively[2].

• UNSPSC :

  12352005

• Target :

  Others

• Type :

  Natural Products

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/sempervirine.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C1([N-]C2=C3C=CC=C2)=C3C=C[N+]4=CC5=C(CCCC5)C=C41

• Molecular Formula :

  C19H16N2

• Molecular Weight :

  272.34

• References & Citations :

  [1]Noriyuki Kogure, et al. Total synthesis and full NMR assignment of ourouparine, a yohimbane-type indole alkaloid isolated from Gelsemium sempervirens. Journal of Natural Medicines volume

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [549-92-8]