Sempervirine

• UNSPSC Description:

  Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC50 values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively[2].

• Target Antigen:

  Others

• Type:

  Natural Products

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/sempervirine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C1([N-]C2=C3C=CC=C2)=C3C=C[N+]4=CC5=C(CCCC5)C=C41

• Molecular Weight:

  272.34

• References & Citations:

  [1]Noriyuki Kogure, et al. Total synthesis and full NMR assignment of ourouparine, a yohimbane-type indole alkaloid isolated from Gelsemium sempervirens. Journal of Natural Medicines volume

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  549-92-8