C30(ω-hydroxy) Ceramide (d18:1/30:0)

• UNSPSC Description:

  C30(ω-hydroxy) Ceramide (d18:1/30:0), a sphingolipid, is an epidermis-specifically vital component of the water barrier in mammalian skin. C30(ω-hydroxy) Ceramide (d18:1/30:0) is expressed in epidermal keratinocytes and male germ cells during their differentiation and maturation. C30(ω-hydroxy) Ceramide (d18:1/30:0) deficiency in the epiderm of Elovl4 deletion or mutation mice[1][2].

• Target Antigen:

  Others

• Type:

  Natural Products

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/c30-ω-hydroxy-ceramide-d18-1-30-0.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC)CCCCCCCCCCCCCCCCCCCCCCCCCCCCCO

• Molecular Weight:

  750.27

• References & Citations:

  [1]Jennemann R, et al. Integrity and barrier function of the epidermis critically depend on glucosylceramide synthesis. J Biol Chem. 2007 Feb 2;282(5):3083-94.|[2]Sandhoff R. Very long chain sphingolipids: tissue expression, function and synthesis. FEBS Lett. 2010 May 3;584(9):1907-13.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  457100-08-2