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JP83

CAT: 0804-HY-111199Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111199Size:1 mg
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Description
JP83 is an irreversible fatty acyl amide hydrolase (FAAH) inhibitor with an IC50 of 1.6 nM in competitive activity-based protein profiling (ABPP) experiments[1].
CAS Number
887264-44-0
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
FAAH
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/jp83.html
Purity
99.0
Solubility
DMSO : 30 mg/mL (ultrasonic; warming)
Smiles
O=C(NCCCCCCC1=CC=CC=C1)OC2=CC(C3=CC(C(N)=O)=CC=C3)=CC=C2
Molecular Formula
C26H28N2O3
Molecular Weight
416.51
Precautions
H315, H319, H335
References & Citations
[1]Jessica P Alexander, et al. Mechanism of carbamate inactivation of FAAH: implications for the design of covalent inhibitors and in vivo functional probes for enzymes. Chem Biol. 2005 Nov;12 (11) :1179-87.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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