RTA 408

CAT: 0026-B2860-25Size: 25 mgDry Ice: NoHazardous: No
CAT#:0026-B2860-25Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RTA 408 is a synthetic oleanane triterpenoid that activates Nrf2. RTA 408 activates Nrf2 and suppresses nitric oxide and pro-inflammatory cytokine levels in interferon-γ-stimulated RAW 264.7 macrophage cells at low concentrations (≤ 25 nM). It inhibits growth of tumor cells with a GI₅₀ value of 260 ± 74 nM. Topical application of RTA 408 induces cytoprotective genes and protects mice from radiation-induced dermatitis.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months