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L002

CAT: 0026-B2859-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2859-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L002 is an inhibitor of p300 histone acetyltransferase (KAT3B). It shows an IC₅₀ of 1.98 μM against p300 in vitro. It inhibits acetylation of histones, p53 and suppresses STAT3 activation. It is cytotoxic to breast cancer cell lines, especially those derived from triple-negative breast cancer cells. It potently suppresses tumor growth and histone acetylation of MDA-MB-468 xenografts.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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