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Tasquinimod

CAT: 0026-B2855-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2855-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tasquinimod has anti-angiogenic, antitumor and immune-modulatory properties. It shows consistent anti-angiogenic activity in vitro at doses between 10-50 μM. The mechanism of action of tasquinimod is not clear but may involve inhibition of MDSC action, a key immune checkpoint in cancer, inhibition of the hypoxia-induced angiogenic switch through epigenetic regulation of HDAC3/4 interactions, which may delay metastatic progression and engagement of the S100A9 protein. It is under clinical evaluation for use in combination therapy with other systemic agents in prostate cancer and as a single agent in solid tumors.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

Alternative Products

CatalogName
A3860-5Tasquinimod

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