LP99

• Description:

  LP99 is an inhibitor of BRD9 and BRD7 bromodomains. LP99 inhibits the interactions of both BRD7 and BRD9 with histones H3.3 and H4, with IC₅₀ values in the low micromolar range in bioluminescence resonance energy transfer (BRET) assays in HEK293 cells. It also inhibits IL-6 secretion from LPS stimulated THP-1 cells at a concentration of 10 μM.

• Shipping Conditions:

  RT

• Storage Conditions:

  -20ºC

• Shelf Life:

  36 months