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TZ9

CAT: 0026-B2835-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2835-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TZ9 is a triazine analogue inhibitor of human E2 ubiquitin-conjugating enzyme Rad6B/HHR6B. It docks to the Rad6B catalytic site. It inhibits Rad6B-induced histone H2A ubiquitination, downregulates intracellular β-catenin, induces G2-M arrest and apoptosis of human breast cancer MDA-MB-231 cells. It inhibits proliferation of MDA-MB-231 cells with an IC₅₀ of 6 μM.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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